Augmented-Nature-UniProt-MCP-Server

概述

这是一个高质量的 MCP 服务器，通过 26 种专业工具提供对 UniProt 蛋白白质数据库的全面访问。它涵盖核心蛋白质分析、比较和进化分析、结构-功能分析、生物上下文分析、批处理、文献引用和数据导出功能。该服务器使用 TypeScript 构建，包含 Docker 支持，文档完善，有清晰的安装指南、示例和错误处理，并且最近仍有提交，表明项目处于活跃维护状态。

试试问 AI

装完之后，这里有 6 个你可以让 AI 做的事：

• search_proteins

  Search the UniProt database for proteins by name, keyword, or organism.

  试试:Search for insulin proteins in humans试试:Find proteins related to p53 tumor suppressor试试:Search for kinases in mice
• get_protein_info

  Get detailed information for a specific protein by UniProt accession.

  试试:Get detailed information about human insulin试试:Retrieve information for protein accession P01308试试:Tell me about the BRCA1 protein
• search_by_gene

  Search for proteins by gene name or symbol.

  试试:Find proteins associated with the BRCA1 gene试试:Search for proteins from the TP53 gene试试:Show me proteins from the KRAS gene in humans
• get_protein_sequence

  Get the amino acid sequence for a protein.

  试试:Get the amino acid sequence for human insulin试试:Retrieve the sequence for protein P01308试试:Show me the sequence of BRCA1 protein
• get_protein_features

  Get functional features and domains for a protein.

  试试:Get functional domains and features for human insulin试试:Show me the features of protein P01308试试:Analyze the functional domains of BRCA1
• compare_proteins

  Compare multiple proteins side-by-side with sequence and feature analysis.

  试试:Compare human insulin with mouse insulin试试:Compare sequences of BRCA1 and BRCA2 proteins试试:Analyze differences between p53 and p63 proteins
• get_protein_homologs

  Find homologous proteins across different species.

  试试:Find homologs of human insulin in other species试试:Show me proteins homologous to BRCA1 in mice试试:Identify homologous proteins to TP53 in different organisms
• get_protein_structure

  Access 3D structure information from PDB databases.

  试试:Get 3D structure information for human insulin试试:Find PDB entries for BRCA1 protein试试:Show structural data for protein P01308
• get_protein_pathways

  Retrieve associated biological pathways from KEGG and Reactome.

  试试:Show biological pathways involving human insulin试试:Find pathways associated with BRCA1试试:What pathways is protein P01308 involved in
• batch_protein_lookup

  Efficiently process multiple protein accessions at once.

  试试:Process accessions P01308, P04637, and P04651试试:Get information for BRCA1, TP53, and KRAS proteins试试:Retrieve data for insulin-related proteins P01308, P01892, and P01323
• advanced_search

  Perform complex queries with multiple filters like length, mass, organism, and function.

  试试:Search for human proteins with mass between 50-60 kDa and signal peptides试试:Find proteins from bacteria with kinase activity试试:Show me enzymes from human proteins with more than 500 amino acids
• export_protein_data

  Export protein data in specialized formats like GFF, GenBank, EMBL, and XML.

  试试:Export human insulin data in GenBank format试试:Save BRCA1 protein data in GFF format试试:Get protein P01308 in XML format

可对比工具

安装

git clone <仓库-url>
cd uniprot-server

npm install

npm run build

{
  "mcpServers": {
    "uniprot": {
      "command": "node",
      "args": ["/path/to/uniprot-server/build/index.js"],
      "env": {}
    }
  }
}

FAQ

这个 MCP 服务器使用哪些数据源？

该服务器直接集成 UniProt REST API，用于访问 UniProt 数据库中的蛋白质数据、结构、注释和相关信息。

除了 Claude Desktop，我还可以将此服务器与其他 MCP 客户端一起使用吗？

是的，此服务器实现了标准 MCP 协议，可与任何支持 stdio 通信的 MCP 客户端一起使用。

蛋白质数据支持哪些输出格式？

该服务器支持多种输出格式，包括 JSON、TSV、FASTA 和 XML，不同工具支持不同格式，默认使用 JSON。

Augmented-Nature-UniProt-MCP-Server 对比