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clinicaltrialsgov-mcp-server vs filesystem

Side-by-side comparison to help you pick between these two MCP servers.

clinicaltrialsgov-mcp-server
by cyanheads
filesystem
by modelcontextprotocol
Stars★ 71★ 85,748
30d uses
Score4877
Official
Categories
healthcareDeveloper ToolsAI / LLM Tools
File SystemDeveloper ToolsProductivity
LanguageTypeScriptTypeScript
Last committhis monththis month

clinicaltrialsgov-mcp-server · Summary

MCP server providing 7 tools for searching, retrieving, and matching clinical trials from ClinicalTrials.gov API.

filesystem · Summary

A feature-rich MCP server for filesystem operations with dynamic directory access control.

clinicaltrialsgov-mcp-server · Use cases

  • Medical researchers can search for relevant clinical trials based on specific conditions or interventions
  • Healthcare providers can match patient demographics and conditions to recruiting trials
  • Data analysts can explore clinical trial landscapes using count and search tools for research insights

filesystem · Use cases

  • Enable AI models to read and write project files during development
  • Allow Claude or other MCP clients to browse and analyze codebases
  • Provide secure sandboxed access to specific directories for content generation

clinicaltrialsgov-mcp-server · Install

Installation

Public Hosted Instance

A public instance is available at https://clinicaltrials.caseyjhand.com/mcp — no installation required. Point any MCP client at it via Streamable HTTP:

{
  "mcpServers": {
    "clinicaltrialsgov-mcp-server": {
      "type": "streamable-http",
      "url": "https://clinicaltrials.caseyjhand.com/mcp"
    }
  }
}

Self-Hosted / Local

Add to your MCP client config (e.g., claude_desktop_config.json):

{
  "mcpServers": {
    "clinicaltrialsgov-mcp-server": {
      "type": "stdio",
      "command": "bunx",
      "args": ["clinicaltrialsgov-mcp-server@latest"],
      "env": {
        "MCP_TRANSPORT_TYPE": "stdio"
      }
    }
  }
}

Prerequisites

  • [Bun v1.3.0](https://bun.sh/) or higher (or Node.js >= 24.0.0)

filesystem · Install

Installation

Using NPX

{
  "mcpServers": {
    "filesystem": {
      "command": "npx",
      "args": [
        "-y",
        "@modelcontextprotocol/server-filesystem",
        "/path/to/allowed/directory"
      ]
    }
  }
}

Using Docker

{
  "mcpServers": {
    "filesystem": {
      "command": "docker",
      "args": [
        "run",
        "-i",
        "--rm",
        "--mount", "type=bind,src=/path/to/allowed/dir,dst=/projects/allowed/dir",
        "mcp/filesystem",
        "/projects"
      ]
    }
  }
}

VS Code Extension

Click the installation buttons in the README to install directly in VS Code.

Comparison generated from public README + GitHub signals. Last updated automatically.