ChEMBL-MCP-Server vs filesystem

Side-by-side comparison to help you pick between these two MCP servers.

	ChEMBL-MCP-Server by Augmented-Nature	filesystem by modelcontextprotocol
Stars	★ 83	★ 85,748
30d uses	—	—
Score	48	77
Official	—	✓
Categories	DatabaseAI / LLM ToolsDeveloper Tools	File SystemDeveloper ToolsProductivity
Language	JavaScript	TypeScript
Last commit	5 mo ago	this month

ChEMBL-MCP-Server · Summary

A comprehensive MCP server providing 22 specialized tools for ChEMBL chemical database access in drug discovery research.

filesystem · Summary

A feature-rich MCP server for filesystem operations with dynamic directory access control.

ChEMBL-MCP-Server · Use cases

Drug discovery researchers querying bioactivity data for specific targets
Chemists searching for compounds with specific structural properties
AI systems performing integrated analysis of chemical data through MCP

filesystem · Use cases

Enable AI models to read and write project files during development
Allow Claude or other MCP clients to browse and analyze codebases
Provide secure sandboxed access to specific directories for content generation

ChEMBL-MCP-Server · Install

Installation

Prerequisites

Node.js (v16 or higher)
npm or yarn

Setup

Clone the repository:

git clone <repository-url>
cd chembl-server

Install dependencies:

npm install

Build the project:

npm run build

Adding to Claude Desktop

Add the server to your Claude Desktop MCP configuration:

{
  "mcpServers": {
    "chembl": {
      "command": "node",
      "args": ["/path/to/chembl-server/build/index.js"],
      "env": {}
    }
  }
}

filesystem · Install

Installation

Using NPX

{
  "mcpServers": {
    "filesystem": {
      "command": "npx",
      "args": [
        "-y",
        "@modelcontextprotocol/server-filesystem",
        "/path/to/allowed/directory"
      ]
    }
  }
}

Using Docker

{
  "mcpServers": {
    "filesystem": {
      "command": "docker",
      "args": [
        "run",
        "-i",
        "--rm",
        "--mount", "type=bind,src=/path/to/allowed/dir,dst=/projects/allowed/dir",
        "mcp/filesystem",
        "/projects"
      ]
    }
  }
}

VS Code Extension

Click the installation buttons in the README to install directly in VS Code.

Comparison generated from public README + GitHub signals. Last updated automatically.